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Exploring Patterns of Care among American Indian Children with Cancer
Protocol Number: 1-AI-CARE
Status: Open
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REACT: Prevention and Treatment of Vasospasm with Clazosentan A Prospective, Multi-Center, Double-Blind, Randomized, Placebo-Controlled, Parallel-Group, Phase 3 Study to Assess the Efficacy and Safety of Clazosentan in Preventing Clinical Deterioration Due to Delayed Cerebral Ischemia (DCI), in Adult Subjects with Aneurysmal Subarachnoid Hemorrhage (aSAH)
Protocol Number: 10024
Status: Open
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Predictive Value of Pulmonary Artery Acceleration Time, Inflammatory Biomarkers, Endothelin 1, Rho-Kinase and B-Natriuretic Peptide in the Development of Pulmonary Hypertension as a Result of Bronchopulmonary Dysplasia in Very Low Birth Weight Infants: An Observational Pilot Study.
Protocol Number: 10099
Status: Open
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PROSpect: Prone and Oscillation Pediatric Clinical Trial
Protocol Number: 10562
Status: Open
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A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of Oral Ozanimod as Induction Therapy for Moderately to Severely Active Crohn's
Protocol Number: 10600
Status: Open
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A Phase 3, Multicenter, Open-Label Extension Study of Oral Ozanimod for Moderately to Severely Active Crohn's Disease
Protocol Number: 10603
Status: Open
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Does Insulin Sensitivity Impact the Potential of Metformin to Slow Aging
Protocol Number: 10699
Status: Open
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A Multi-Center, Parallel-Group, Randomized Controlled Trial of Frozen Embryo Transfers to Determine Incidence of Preeclampsia and Live Birth Rate in Modified Natural versus Programmed Cycles (NATPRO)
Protocol Number: 10846
Status: Open
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A Randomized, Double Blind Parallel-Group, Placebo Controlled Study to Evaluate the Efficacy and Safety of IBP-9414 in Premature Infants 500-1500g Birth Weight in the Prevention of Necrotizing Enterocolitis
Protocol Number: 10928
Status: Open
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A Phase 3, Multicenter, Randomized, Double-Blind, Placebo- and Active-Controlled, Treat-Through Study to Evaluate the Efficacy and Safety of Mirikizumab in Patients with Moderately to Severely Active Crohns disease
Protocol Number: 11254
Status: Open
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Anticoagulation in Intracerebral Hemorrhage (ICH) Survivors for Stroke Prevention and Recovery
Protocol Number: 11294
Status: Open
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Stress Hydrocortisone in Pediatric Septic Shock
Protocol Number: 11451
Status: Open
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Pharmacokinetics, Pharmcodynamics, and Safety Profile of Understudied Drugs Administered to Children per Standard of Care / (POPS)
Protocol Number: 11513
Status: Open
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Evaluating the Relationship between Ovarian Reserve and Facial Age as Determined by Computer Software in Non-Infertile Population
Protocol Number: 11568
Status: Open
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READY 1: A PHASE 3, RANDOMIZED, DOUBLE-BLIND, ACTIVE AND PLACEBO CONTROLLED STUDY ON THE USE OF CUSA-081 FOR DYSFUNCTIONAL CENTRAL VENOUS ACCESS DEVICES (CVADs)
Protocol Number: 11706
Status: Open
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Idiopathic Pulmonary Fibrosis Prospective Outcomes (IPF-PRO) and Chronic Fibrosing Interstitial Lung Disease with Progressive Phenotype Prospective Outcomes (ILD-PRO) Registry
Protocol Number: 11858
Status: Open
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NeoChip for Specific and Rapid Identification of Congenital CMV and Neonatal HSV Infections on Minimal Sample Volume
Protocol Number: 11866
Status: Open
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StATins Use in intRacereberal hemorrhage patieNts (SATURN)
Protocol Number: 12020
Status: Open
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Myo-Inositol as an Adjuvant to Letrozole for Infertility in PolyCystic Ovary Syndrome (MALIPCOS): A Randomized Pilot Trial
Protocol Number: 12103
Status: Open
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Pilot RCT Intervention Targeting Elevated Triglycerides with a Point-of-Care Meter and Omega-3 Fatty Acids to Normalize Triglycerides and Fetal Growth (TOTS)
Protocol Number: 12185
Status: Open
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A Phase 3, Multicenter, Open-Label Extension Study to Evaluate the Long Term Efficacy and Safety of Mirikizumab in Patients with Modertately to Severely Active Ulcerative Colitis
Protocol Number: 12303
Status: Open
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A Phase 3, Multicenter, Open-Label, Long-Term Extension Study to Evaluate the Long term efficacy and safety of mirikizumab in Patients with Crohn's Disease
Protocol Number: 12658
Status: Open
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Biorepository for Necrotizing Enterocolitis
Protocol Number: 12909
Status: Open
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Miyazaki Enterprises: Phase II B SBIR Human Subjects Protocol Effect of Validated Surgical Skills Simulation with the Miya Model on Operating Room Performance of Vaginal Hysterectomy
Protocol Number: 13165
Status: Open
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A Randomized, Double-blind, Placebo-controlled, Phase 3 Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects with Idiopathic Pulmonary Fibrosis
Protocol Number: 13407
Status: Open
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Mitochondrial Dysfunction as a Cause of Prematurity Associated Cardiac Disease in Preterm Infants: An Observational Cross-Sectional Pilot Study
Protocol Number: 13456
Status: Open
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Impact of Neighborhood and Individual Social Adversity on Outcomes of Critically-Ill Children with Medical Complexity
Protocol Number: 13491
Status: Open
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Migraine and Primary Dysmenorrhea in Adolescence
Protocol Number: 13541
Status: Open
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Large Scale Genome Sequencing and Integrative Analyses to Define Genomic Predictors of Recurrent Pregnancy Loss
Protocol Number: 13681
Status: Open
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Autoimmune Basis for Postural Tachycardia Syndrome
Protocol Number: 13705
Status: Open
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Intensive Glycemic Targets in Overweight and Obese Women with Gestational Diabetes Mellitus: A Multicenter Randomized Trial
Protocol Number: 13812
Status: Open
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EVALUATION OF THE EFFICACY AND SAFETY OF PTC299 IN HOSPITALIZED SUBJECTS WITH COVID-19 (FITE19)
Protocol Number: 13902
Status: Open
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A Pragmatic Randomized Controlled Pilot Trial to Evaluate the Impact of Early Prophylactic CPAP in Spontaneously Breathing Late Preterm Newborn Infants Born by Cesarean Delivery Compared to No CPAP on the Need for Further Respiratory Support Leading to NICU Admissions.
Protocol Number: 13965
Status: Open
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NIH RECOVER: A Multi-site Observational Study of Post Acute Sequelae of SARS-CoV-2 (PASC) Infection in Pediatric Populations
Protocol Number: 13999
Status: Open
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A Randomized, Phase 1, Contemporaneously Controlled,Multicenter Study to Assess the Safety of PP-007 in Subjects with Acute Ischemic Stroke (HEMERA-1)
Protocol Number: 14019
Status: Open
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Hyperhydration to Improve Kidney Outcomes in Children with Shiga Toxin-Producing E. coli Infection: A Multinational Embedded Cluster Crossover Randomized Trial (HIKO STEC)
Protocol Number: 14032
Status: Open
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A 3D Human Tissue-Engineered Lung Model to Study Immune Responses to Respiratory Syncytial Virus
Protocol Number: 14051
Status: Open
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A Long-term Safety Study to Assess the Potential for Chronic Liver Injury in Participants Treated with Epidiolex (Cannabidiol) Oral Solution
Protocol Number: 14081
Status: Open
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Oklahoma Preterm Biorepository
Protocol Number: 14187
Status: Open
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WGS as A First-Tier Test in Infant Extracorporeal Life Support
Protocol Number: 14228
Status: Open
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A Phase 3 open-label extension (OLE) study to evaluate the long-term safety and efficacy of ralinepag in subjects with World Health Organization (WHO) Group 1 pulmonary arterial hypertension (PAH) (ADVANCE Extension)
Protocol Number: 14296
Status: Open
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Shift From Unilateral to Bilateral Sensory-Motor Connectivity in Chronic Hemiparetic Stroke
Protocol Number: 14309
Status: Open
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Role of Hydrogen Sulfide Machinery in Neonatal Airway Epithelial Programming
Protocol Number: 14377
Status: Open
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Vascular Mechanisms Leading to Progression of Mild Cognitive Impairment to Dementia After COVID-19
Protocol Number: 14585
Status: Open
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The Effect of NAD Supplementation on Brain Vascular Health in Aging
Protocol Number: 14782
Status: Open
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Determine the Effect of Targeted High-Definition tDCS on Reducing Post-Stroke Upper Limb Motor Impairments
Protocol Number: 14906
Status: Open
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Catheter-Related Early Thromboprophylaxis with Enoxaparin (CRETE) Studies
Protocol Number: 14920
Status: Open
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A PHASE 3, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY TO EVALUATE THE EFFICACY AND SAFETY OF INTRAVENOUS EFZOFITIMOD IN PATIENTS WITH PULMONARY SARCOIDOSIS
Protocol Number: 14964
Status: Open
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An Open-label Extension Study of Inhaled Treprostinil in Subjects with Idiopathic Pulmonary Fibrosis
Protocol Number: 14966
Status: Open
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Examining the Effects of Intrapartum Antibiotic Prophylaxis (IAP) for Group B Streptococcus (GBS) on Maternal Pro-inflammatory Cytokine levels throughout Labor Induction
Protocol Number: 15028
Status: Open
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Pregnancy as a Window to the Future: Outcomes of Antihypertensive Therapy and Superimposed Preeclampsia in Pregnant Women with Mild Chronic Hypertension
Protocol Number: 15079
Status: Open
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A Phase III, Multicentre, Randomised, Double-blind, Chronic-dosing, Parallel-group, Placebo-controlled Study to Evaluate the Efficacy and Safety of Two Dose Regimens of MEDI3506 in Participants with Symptomatic Chronic Obstructive Pulmonary Disease (COPD) with a History of COPD Exacerbations (TITANIA)
Protocol Number: 15201
Status: Open
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The Effect of Gabapentin on Post-Operative Pain in Minimally Invasive Sacrocolpopexy: A Randomized Controlled Pilot Study
Protocol Number: 15207
Status: Open
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A 52-week, randomized, double-blind, double-dummy, placebo- and active- controlled (Roflumilast, Daliresp® 500µg), parallel group, study to evaluate the efficacy and safety of two doses of CHF6001 DPI add-on to maintenance triple therapy in subjects with Chronic Obstructive Pulmonary Disease (COPD) and chronic bronchitis.
Protocol Number: 15240
Status: Open
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The effect of intermittent fasting on cellular rejuvenation
Protocol Number: 15436
Status: Open
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Comparison of Anti-Coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis (CAPTIVA)
Protocol Number: 15508
Status: Open
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Urolithin A Supplementation to Improve Endothelial and Cerebrovascular Function in Middle-Aged Adults with Obesity
Protocol Number: 15561
Status: Open
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Theophylline Prophylaxis During Hypothermia to Limit Neonatal Nephron Damage
Protocol Number: 15569
Status: Open
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A Multicenter, International, Randomized, Placebo Controlled, Double-Blind, Parallel Group and Event Driven Phase 3 Study of the Oral FXIa Inhibitor Asundexian (BAY 2433334) for the Prevention of Ischemic Stroke in Male and Female Participants Aged 18 Years and Older After an Acute Non-Cardioembolic Ischemic Stroke or High-Risk TIA (OCEANIC)
Protocol Number: 15579
Status: Open
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IV Ensure in Patients Receiving OPAT
Protocol Number: 15857
Status: Open
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Phase 2, Proof-Of-Concept, Randomized, Double-Blinded, Placebo-Controlled, Multicenter Study to Assess Efficacy and Safety of Reparixin as Add-On Therapy to Standard Of Care in Adult Patients with Acute Respiratory Distress Syndrome (RESPIRATIO)
Protocol Number: 15908
Status: Open
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A Two-Cohort, Phase II, Multicenter, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Study Evaluating the Efficacy and Safety of Vixarelimab Compared with Placebo in Patients with Idiopathic Pulmonary Fibrosis and in Patients with Systemic Sclerosis Associated Interstitial Lung Disease
Protocol Number: 15924
Status: Open
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A Randomized, Placebo-Controlled, Double-Blind, Multi-Center, Phase III Trial to Assess the Efficacy and Safety of Trimodulin (BT588) in Adult Hospitalized Subjects with Severe Community-Acquired Pneumonia (sCAP)
Protocol Number: 16039
Status: Open
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Impact of Obesity on Disease Activity of Patients with Rheumatoid Arthritis (Obesity in RA)
Protocol Number: 16066
Status: Open
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Time restricted eating for prevention of age-related vascular cognitive decline in older adults
Protocol Number: 16102
Status: Open
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A Phase 3, Multicenter, Randomized, Double-Blind Study of the Efficacy and Safety of Rezafungin for Injection Versus the Standard Antimicrobial Regimen to Prevent Invasive Fungal Diseases in Adults Undergoing Allogeneic Blood and Marrow Transplantation
Protocol Number: 16258
Status: Open
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The Effects of a Novel, Non-ischemic and Pain-free Exercise Intervention in Peripheral Artery Disease (NICE)
Protocol Number: 16294
Status: Open
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Randomized, Double-Blind, Placebo-Controlled Proof-of-Concept Study to Evaluate the Efficacy, Safety and Tolerability of Efzofitimod in Patients With Systemic Sclerosis Related Interstitial Lung Disease
Protocol Number: 16338
Status: Open
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Optimization of Saturation Targets and Resuscitation (OptiSTART): Multicenter Randomized Controlled Trial
Protocol Number: 16373
Status: Open
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The Effects of Diet and Exercise Interventions in Peripheral Artery Disease
Protocol Number: 16383
Status: Open
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Thrombopoiesis in Diabetes: Role of Damage Associated Molecular Patterns
Protocol Number: 16497
Status: Open
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The REBALANCE Study: A Prospective, Multicenter, Randomized, Pivotal Study of the May Health System in Transvaginal Ablation of Ovarian Tissue Under Ultrasound Guidance in Women With Infertility due to Polycystic Ovary Syndrome
Protocol Number: 16578
Status: Open
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MagicTouchTM Sirolimus-Coated Balloon for Treatment in Coronary Artery Lesions of In-Stent Restenosis.
Protocol Number: 16584
Status: Open
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Selective Early Medical Treatment of the Patent Ductus Arteriosus in Extremely Low Gestational Age Infants: A Pilot Randomized Controlled Trial
Protocol Number: 16663
Status: Open
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A Phase IIa, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of INS018_055 Administered Orally to Subjects with Idiopathic Pulmonary Fibrosis (IPF)
Protocol Number: 16709
Status: Open
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A Randomized, Double-Blind, Dose-Ranging, Placebo-Controlled Study to Evaluate the Efficacy and Safety of PLN-74809 (Bexotegrast) for the Treatment of Idiopathic Pulmonary Fibrosis (BEACON)
Protocol Number: 16713
Status: Open
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Acute Stress in Ischemic Stroke Trial
Protocol Number: 16793
Status: Open
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A Multicenter, Randomized, Double-blind, Placebo-controlled, Phase 3 Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986278 in Participants with Progressive Pulmonary Fibrosis
Protocol Number: 16822
Status: Open
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The Role of Sex Hormones in Adaptive Immunity: Implications for Menopausal Weight Gain
Protocol Number: 16859
Status: Open
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A Phase 3b Study to Evaluate the Duration of Effect of Bimatoprost SR in Participants with Open-Angle Glaucoma or Ocular Hypertension
Protocol Number: 1698-301-007
Status: Open
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Diabetic Dyslipidemia and Cholesterol Crystal (CC) in Pathogenesis of Preeclampsia
Protocol Number: 16983
Status: Open
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A Randomized, Controlled, Phase 1-2 Open Label Study of ST266 IV Administration to Assess the Safety, Tolerability, and Preliminary Efficacy of ST266 in Infants with Necrotizing Enterocolitis
Protocol Number: 17226
Status: Open
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Offspring Neurodevelopment and Growth After Early Antihypertensive Therapy or Preeclampsia in Women With Chronic Hypertension and Pregnancy (CHAP Child)
Protocol Number: 17331
Status: Open
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A Phase 2b, Multicenter, Randomized, Open-Label, Two-Arm Study to Evaluate the Clinical Efficacy and Safety of OHB-607 Compared to Standard Neonatal Care for the Prevention of Bronchopulmonary Dysplasia, the Most Common Cause of Chronic Lung Disease of Prematurity
Protocol Number: 17369
Status: Open
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Antibiotic Prophylaxis to Prevent Obesity-Related Induction Complications in Nulliparae at Term 2.0 (APPOINT 2.0): A multi-center randomized controlled trial
Protocol Number: 17420
Status: Open
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Continuous Glucose Monitoring for Gestational Diabetes: An Ancillary Study to the iGDM Trial
Protocol Number: 17639
Status: Open
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URBan Native Elders (URBANE): Risk and Protective Factors for Alzheimer's and Related Dementias
Protocol Number: 18147
Status: Open
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United States Thrombotic Microangiopathy (USTMA) Thrombotic Thrombocytopenic Purpura (TTP) Clinical Data and Biologic Sample Repository
Protocol Number: 2015H0387
Status: Open
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The Effects of Very Long Chain Polyunsaturated Fatty Acids on Fertility and Sperm Function
Protocol Number: 4191
Status: Open
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Effectiveness and Safety of Small Aneurysm Coiling Trial (NANO)
Protocol Number: 5053
Status: Open
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Serum Biomarkers of the Ischemic Stroke Core in Patients with Large Vessel Occlusion
Protocol Number: 5349
Status: Open
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A Multicenter Safety Study of Unlicensed, Investigational Cryopreserved Cord Blood Units Manufactured by the National Cord Blood Program and Provided for Unrelated Hematopoietic Stem Cell Transplantation of Pediatric and Adult Patients
Protocol Number: 6637-01
Status: Open
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A Phase 3, Randomized, Double-Blind, Double-Dummy, Parallel Group, Active-Controlled Study to Evaluate the Efficacy and Safety of Milvexian, an Oral Factor XIa Inhibitor, Versus Apixaban in Participants with Atrial Fibrillation
Protocol Number: 70033093AFL3002
Status: Open
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A Randomized Controlled Trial to Evaluate Growth Velocity and Clinical Outcomes of Infants with Single Ventricle Physiology Fed an Exclusive Human Milk Diet with Early Nutritional Fortification Following Surgical Repair
Protocol Number: 7043
Status: Open
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Early MiNimally-invasive Removal of ICH
Protocol Number: 7334
Status: Open
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Ruptured Aneurysms Treated with Hydrogel Coils
Protocol Number: 8727
Status: Open
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AtRial Cardiopathy and Antithrombotic Drugs In Prevention After Cryptogenic Stroke
Protocol Number: 8942
Status: Open
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Progression of Urinary Symptoms After Bariatric Surgery
Protocol Number: 9422
Status: Open
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Randomized Trial of Laparoscopic Sacrocolpopexy with Posterior Repair to Reduce Obstructed Defecation Symptoms
Protocol Number: 9457
Status: Open
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A Phase 3, Multicenter, Open-Label Extension Trial of Oral RPC1063 as Therapy for Moderate to Severe Ulcerative Colitis
Protocol Number: 9596
Status: Open
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